Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to valid methods and considered reliable, adequate and relevant.
Data source
Reference
- Reference Type:
- publication
- Title:
- Experimental Carcinogenicity and Acute Toxicity Of Representative Epoxide
- Author:
- Weil C. S., Condra N., Haun C. and Striegel J. A.
- Year:
- 1 963
- Bibliographic source:
- American Industrial Hygiene Association Journal, 24:4, 305-325, DOI: 10.1080/00028896309343226
Materials and methods
- Principles of method if other than guideline:
- No data
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 2-ethylhexyl 3-octyloxiran-2-octanoate
- EC Number:
- 205-482-8
- EC Name:
- 2-ethylhexyl 3-octyloxiran-2-octanoate
- Cas Number:
- 141-38-8
- IUPAC Name:
- 2-ethylhexyl 8-(3-octyloxiran-2-yl)octanoate
- Reference substance name:
- 2-EH stearate mono-epoxidized
- IUPAC Name:
- 2-EH stearate mono-epoxidized
- Test material form:
- other: liquid
- Details on test material:
- - Name of test material (as cited in study report): 2-Ethylhexyl 9,10-epoxystearate
- Substance type: UVCB
Constituent 1
Constituent 2
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 30.8 mL/kg bw
- Based on:
- test mat.
- 95% CL:
- > 24.9 - < 38.1
Applicant's summary and conclusion
- Conclusions:
- The oral LD50 of 2-Ethylhexyl 9,10-epoxystearate (EMS) in rats was 30.8 mL/kg bw.
- Executive summary:
The oral LD50 of 2-Ethylhexyl 9,10-epoxystearate (EMS) in rats was 30.8 mL/kg bw.
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