Registration Dossier
Registration Dossier
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EC number: 255-449-7 | CAS number: 41583-09-9
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
Classification, Labelling, and Packaging Regulation (EC) No 1272/2008
The substance is of low ecotoxicity. The LC50/EC50 values for the dissociation products melamine and phosphate are well above 100 mg/L. Furthermore, the chronic toxicity study to Daphnia magna did not reveal effects up to a test substance concentration of 10 mg/L. The substance has a very low log Kow (log Kow: -3 at 25 °C). There are no indications for a classification of melamine, based on ecotoxicity and/or fate and behaviour in the environment. The substance is not a PBT or vPvB-substance, because of the low bioconcentration potential, the low partition coefficient n-octanol/water and the low ecotoxicity.
In conclusion, the available experimental test data are reliable and suitable for classification purposes under Regulation (EC) No 1272/2008. No studies on biodegradation were performed with the test substance. A reliable read across justification with melamine (CAS 108-78-1) was performed (see section 13 of IUCLID). The surrogate test substance melamine (CAS 108-78-1) was found to be not readily biodegradable under the test conditions. In addition, the most sensitive test for the aquatic compartment was the toxicity test to aquatic invertebrates. This study revealed a 48h-EC50 of 200 mg/L for the surrogate test substance melamine (CAS 108-78-1). In addition the 22d-NOEC of a long-term toxicity test to aquatic invertebrates with the test substance was determined to be 10 mg/L. Based on these results, the substance is neither classified as aquatic acute toxicity nor classified as aquatic chronic according to table 4.1.0 of Annex I of Regulation (EC) No 1272/2008 and according to Regulation (EC) No 1272/2008 (CLP) as amended for the tenth time in Commission Regulation (EU) 2017/776.
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