Registration Dossier
Registration Dossier
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EC number: 210-871-0 | CAS number: 624-92-0
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- 0.97 mg/L
Additional information
Acute toxicity of DMDS to fish has been assessed using different fish species.
Acute toxicity to Rainbow trout (Oncorhynchus mykiss) has been investigated through EPA OPPTS Draft Guideline 850.1075 (1996). Oncorhynchus mykiss were exposed for 96 hours to an aqueous solution of dimethyl disulfide at different nominal concentrations of 0.625 - 1.25 - 2.5 - 5 and 10 mg/L. LC 50 - 96h determined is of 0.97 mg/L and NOEC - 96h is 0.541 mg/L.
Acute toxicity to Zebrafish (Danio rerio) has been investigated through EPA OPPTS Draft Guideline 850.1075 (1996).
Danio rerio were exposed for 96 hours to an aqueous solution of dimethyl disulfide at different nominal concentrations of 6.25 - 12.5 - 25 - 50 and 100 mg/L. LC 50 - 96h determined is of 5.01 mg/L and NOEC - 96h is 3.3 mg/L.
Acute toxicity to Cyprinodon variegatus has been investigated through EPA OPPTS 850.1075; U.S. Environmental Protection Agency Standard Evaluation Procedure for Acute Toxicity Test for Estuarine and Marine Organisms and ASTM Standard E729-96.
Cyprinodon variegatus were exposed for 96 hours to an aqueous solution of dimethyl disulfide at different nominal concentrations of 2.6 - 4.3 - 7.2 - 12 and 20 mg active ingredient (a.i.)/L. LC 50 - 96h determined is of 5.6 mg/L and NOEL - 96h is < 2.3 mg/L.
With one LD50 slightly below 1.00 mg/l DMDS has to be considered as very toxic to fish.
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