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EC number: 203-851-8 | CAS number: 111-26-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The test substance was considered to be readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Based on a weight-of-evidence-approach using QSAR-data as well as experimentally derived data from two analogous compounds hexylamine is considered to be readily biodegradable.
QSAR-models for predicting biodegradability of n-hexylamine:
The following QSAR-models were used to predict the ready biodegradability of the test substance:
- BIOWIN v4.10 (EPI Suite v4.11) (substance is within applicability domain of the model): substance is readily biodegradable
- CATALOGIC (v5.11.15) BOD 28 days MITI (OECD 301C) v08.11 - July, 2014: substance is readily biodegradable
- CATALOGIC (v5.11.15) CO2 Kinetic (OECD 301B) v02.08 - July, 2014: substance is readily biodegradable
- CATALOGIC (v5.11.15) BOD Kinetic (OECD 301F) v11.14 - July, 2014: substance is readily biodegradable, failing 10 -d window
Experimentally derived data from read-acorss substances:
Data on structural analogue substances are available which were used in a read across approach.
- Monobutylamine (CAS-# 109 -73 -9):
For Monobutylamine, publications are available describing study results obtained in a modified MITI test (according OECD Guideline 301 C). Activated sludge was exposed to 100 mg/L of the read across substance for a duration of 14 days under aerobic conditions. Based on O2 consumption (BOD/ThOD), the degradation was determined to be 85 % (not including NH3 oxidation) and the substance therefore considered to be readily biodegradable.
- Octylamine (CAS-# 111 -86 -4):
In a study conducted according to OECD guideline 301A, activated sludge (domestic) was exposed to 32 mg/L Octylamine (read across substance) for 11 days in an aerobic system. As parameter of biodegradation, DOC removal was measured. As a result, after 11 days the degradation rate was determined to be 99 % based on DOC removal. For the positive control substance aniline a degradation rate of 98 % after 11 days was observed. Therefore Octylamine was concluded to be readily biodegradable.
Taken together the available data, it was concluded that the test substance is readily biodegradable.
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