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EC number: 601-409-2
CAS number: 116020-44-1
For eleven common liquid crystalline structures a category of typical compounds was established sharing chemical structural aspects, physicochemical properties and biological responses in assays for aquatic toxicity.
The query compound fulfils the category criteria for the chemical applicability domain, the physiochemical space and the biological response in the aquatic toxicity assays.
In short term test in Daphnia and in long term tests in fish the query compound shows NOECs above the water solubility limit.
Based on these data the category provides sufficient and reliable information to fill the data gap for the long term toxicity testing on invertebrates, i.e. Daphnia Magna Reproduction Test.
In conclusion, there is sufficient and reliable evidence from the chemical category and for the query compound itself to conclude that the test material is not toxic to aquatic species in acute and in long term settings up the limit of water solubility. Therefore the data requirement according to REACH Annex IX, 9.1.5 is fulfilled and no further experimental testing is considered justified.
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