Registration Dossier

Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Dose descriptor:
NOAEL
43.6 mg/kg bw/day
Additional information

This value is obtained in males based on the food consumption.


Short description of key information:
A 1-generation study has been performed, the NOAEL for the F1 and P generations is 600 ppm.

Effects on developmental toxicity

Effect on developmental toxicity: via oral route
Dose descriptor:
NOAEL
100 mg/kg bw/day
Additional information

The effects observed in this study are statistically significant but are in the range of historical variations. So they are not considered as related to the treatment.

Justification for classification or non-classification

The substance has not been classified for reproduction effects by the ECB.