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Toxicity to microorganisms

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activated sludge respiration inhibition testing
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
Justification for type of information:
According to REACH Annex XI Section 1 (“The study is scientifically not necessary; other information available”) no study on the toxicity to microorganisms has to be conducted. Following REACH Annex XI Section 1.2 “Weight of Evidence” other information is available that is reliable and sufficient to cover the endpoint of toxicity to microorganisms according to REACH Annex VIII Section 9.1.1 Column 1.

According to the ECHA Guidance document R7b, no further test on the toxicity to microorganisms has to be conducted if the toxicity control in a ready biodegradability test shows no inhibitory effects on microorganisms. As the toxicity control in the ready biodegradability test showed no inhibition of the microbial activity at the highest feasible substance concentration of 2 mg/L, no further test is necessary to evaluate the respiration inhibition of activated sludge. The concentration used in the toxicity control (2 mg/L) can be used as NOEC value.

Description of key information

In a ready biodegradability test no toxic effects to microorganisms were observed after incubation with the highest feasible concentration of 2 mg/L test substance.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
2 mg/L

Additional information