Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

Local lymph node assay (LLNA) study (Bradshaw 2012) showed positive responses at 25, 50, and 100% concentrations. There was sufficient dose response to calculate an EC3 value of 20%.

Migrated from Short description of key information:

Local lymph node assay (LLNA) study (Bradshaw 2012) showed positive responses at 25, 50, and 100% concentrations. EC3 value was determined to be 20%.

Justification for classification or non-classification

Classified as a skin sensitizer based on the positive LLNA study.