Registration Dossier

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
explosive properties of explosives
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-09-13 to 2018-01-31
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
UN Manual of Tests and Criteria: Part I: Classification procedures, test methods and criteria relating to explosives of Class 1
Deviations:
no
GLP compliance:
yes (incl. certificate)
Key result
Parameter:
other: exothermic decomposition
Remarks on result:
other: no exothermic decomposition was detected up to 500°C
Interpretation of results:
GHS criteria not met
Conclusions:
In the DSC-measurement no exothermic decomposition of the test item Tetrahydrofolic acid could be observed up to a temperature of 500 °C. Therefore, further tests for explosive properties did not have to be performed.
According to the results of the test on thermal stability, the test item is classified as follows:
UN Transport Regulation: The test item does not have to be classified as explosive substance in class 1 according to the UN Transport Regulation.
GHS (CLP Regulation EC 1272/2008: Annex 1: 2.1): The test item does not have to be classified as explosive substance according to GHS or CLP Regulation EC 1272/2008 Annex 1: 2.1, respectively.

Description of key information

Explosiveness: non explosive (UN Manual of Tests and Criteria: Part I, GLP)

Key value for chemical safety assessment

Explosiveness:
non explosive

Additional information

In the DSC-measurement no exothermic decomposition of the test itemTetrahydrofolic acid could be observed up to a temperature of 500 °C. Therefore, further tests for explosive properties did not have to be performed.

Justification for classification or non-classification

Based on the available data, tetrahydrofolic acid does not meet the classification criteria for explosive solids according to Regulation (EC) No. 1272/2008 (CLP) and the Globally Harmonized System of Classification of Chemicals (GHS).