Registration Dossier
Registration Dossier
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EC number: 205-181-1 | CAS number: 135-16-0
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-09-13 to 2018-01-31
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions) - Method B: Fibre Length and Diameter Distributions
- Version / remarks:
- January 21, 1998
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Version / remarks:
- 2009
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- mass based distribution
- Remarks on result:
- not measured/tested
- Key result
- Percentile:
- D10
- Mean:
- 8.1 µm
- Remarks on result:
- other: Standard deviation was not determined.
- Key result
- Percentile:
- D50
- Mean:
- 22.4 µm
- Remarks on result:
- other: Standard deviation was not determined
- Key result
- Percentile:
- D90
- Mean:
- 37.3 µm
- Remarks on result:
- other: Standard deviation was not determined
- Conclusions:
- The test item Tetrahydrofolic acid has a median particle size D50 = 22 µm, which was determined by laser diffraction measurement, according to ISO 13320 and OECD 110.
Reference
Description of key information
Particle size distribution: D50 = 22.4 µm (OECD 110, GLP)
Additional information
The test item Tetrahydrofolic acid has a median particle size D50 = 22 µm, which was determined by laser diffraction measurement, according to ISO 13320 and OECD 110.
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