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Surface tension

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Reference
Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018-01-05 to 2018-02-16
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 115 (Surface Tension of Aqueous Solutions)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.5 (Surface Tension)
Version / remarks:
2008
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
OECD harmonised ring method
Key result
Surface tension:
64.75 mN/m
Temp.:
20.1 °C
Conc.:
1 g/L

Table 1: Surface Tension; Temperature

Measurement No 1)

Time 2)

[min]

Time 3)

[min]

Surface Tension [mN/m]

Temperature

1

103.25

55.72

64.67

20.1

2

104.00

56.47

64.69

20.1

3

104.76

57.22

64.71

20.1

4

105.51

57.97

64.75

20.1

5

106.26

58.72

64.75

20.1

6

107.01

59.47

64.75

20.1

7

107.76

60.23

64.76

20.1

8

108.51

60.97

64.82

20.1

9

109.25

61.72

64.81

20.1

10

110.oo

62.47

64.80

20.1

Mean

 

 

64.75

20.1

SD [±]

 

 

0.05

0.0

SD = standard deviation

1 )   of the last 10 measurements

2)        Time from preparation of test solution in the test vessel until end of each measurement

3)        Time from start of measurement until end of each measurement

Conclusions:
The surface tension of a 1 g/L (saturated) aqueous solution of the test item Tetrahydrofolic acid was determined to be 64.75 mN/m (standard deviation e 0.05 mN/m) at 20 °C, Considering that distilled water has a surface tension of 72.75 mN/m at 20 °C and the test item showed a surface tension above 60 mN/m under the conditions of this referring method, the test item should be regarded as being not surface-active material.

Description of key information

Surface tension: 64.75 mN/m at 20°C (OECD 115, GLP)

Key value for chemical safety assessment

Surface tension:
64.75
in mN/m at 20°C and concentration in mg/L:
1 000

Additional information

The surface tension of a 1 g/L (saturated) aqueous solution of the test item Tetrahydrofolic acid was determined to be 64.75 mN/m (standard deviation e 0.05 mN/m) at 20 °C, Considering that distilled water has a surface tension of 72.75 mN/m at 20 °C and the test item showed a surface tension above 60 mN/m under the conditions of this referring method, the test item should be regarded as being not surface-active material.