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EC number: 248-130-9
CAS number: 26952-13-6
a primary dermal irritation study, 3New Zealand WhiteRabbits were
dermally exposed to 0.5mL of SHOP C68 Internal Olefin for 4 hours on
3x2cm semi-occluded clipped area on the dorsum. Animals
then were observedat 1, 24, 48, and 72
hours and 7,10, and 13 days after exposure. Irritation
was scored by the method of Draize criteria.
animals had very slight to slight erythema, which sometimes extended
beyond the test site, and occasionally very slight edema for the first
72 hours post exposure. The
study authors concluded that under the study conditions, SHOP C68
internal olefin was slightly irritating to rabbit skin; however, the
test material is not considered to be irritating under EU criteria.
study received a Klimisch score of 1 and is classified as reliable
without restrictionbecause it was
conducted according to GLP guidance and according to OECD 404 guidelines.
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