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EC number: 248-130-9
CAS number: 26952-13-6
In an acute
percutaneous toxicity study, groups of young Wistar rats, 4 male and 4
female, were dermally exposed to undiluted Internal Olefin 114 LP11 for
24 hours at doses of 1, 2, and 4 mL/kg bw. Animals
then were observed for 9 days.
Three males died at the 4.0 mL/kg dose
level. This rats who died were noted to not eat or drink thus losing a
considerable amount of body weight. No other deaths were reported. The
acute percutaneous LD50 of Internal Olefin 114 LP11 in rats was greater
than 4 mL/kg (i.e., 3040 mg/kg) in females and between 2 and 4 mL/kg (i.e.,
1520 to 3040 mg/kg) in males.
This study received a Klimisch score of 2
and is classified as reliable with restriction because although it is an
acceptable and well documented study report a GLP statement was not
provided and details regarding the test material and animal husbandry
was not provided.This
study will influence the DNEL(s).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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