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EC number: 255-062-3 | CAS number: 40754-59-4
Endpoint summary
Administrative data
Description of key information
Bioaccumulation: aquatic / sediment:
From BCFBAF Program (v3.00) model of EPI suite the estimated bio concentration factor (BCF) for 4-oxo-2-sulfonato-5,8,11,14-tetraoxahexacosan-1-oate is 70.79 L/kg wet-wt which does not exceed the bioconcentration threshold of 2000.Thus it is concluded that chemical 4-oxo-2-sulfonato-5,8,11,14-tetraoxahexacosan-1-oate is not expected to be bioaccumulative in fish and the food chain.
Additional information
Bioaccumulation: aquatic / sediment:
Two studies including those from validated prediction database and experimental study for bioaccumulation endpoint of target chemical disodium 4-oxo-2-sulfonato-5, 8, 11, 14-tetraoxahexacosan-1-oate (Cas no. 40754-59-4) and relevant read across which is structurally similar to the target chemical are summarized as followed:
First study reports prediction done using the BCFBAF (v3.00) model of EPI Suite program, which indicated the estimated bio concentration factor (BCF) for disodium 4-oxo-2-sulfonato-5, 8, 11, 14-tetraoxahexacosan-1-oate as 70.79 L/kg wet-wt which does not exceed the bioconcentration threshold of 2000.
Above prediction for target supported by an experimental study of structurally similar read across bis(2-(2-butoxyethoxy)ethyl) adipate (Cas no. 141-17-3) suggested an estimated BCF of 62 was calculated for bis(2(2butoxyethoxy)ethyl) adipate, using an estimated log Kow of 3.24 and a regression derived equation. This BCF suggests the potential for bioconcentration in aquatic organisms is low. (HSDB database; 2017)
Both values for bioaccumulation is in the range of 62 -70.79 (L/kg or dimensionless) which conclude that the target chemical disodium 4-oxo-2-sulfonato-5, 8, 11, 14-tetraoxahexacosan-1-oate (Cas no. 40754-59-4) is not expected to be bioaccumulative in fish and the food chain.
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