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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The 96-h LC50 in the freshwater fish Oncorhynchus mykiss is 52 mg/l. The 96 h LC50 is 89 mg/L in the marine fish species Mugil cephalus.

Key value for chemical safety assessment

LC50 for freshwater fish:
52 mg/L
LC50 for marine water fish:
89 mg/L

Additional information

A GLP-compliant guideline study (EPA-660/3-75-009) is available for propylene oxide, reporting a 96 h LC50 value of 52 mg/L in the freshwater species Salmo gairdneri (new name: Oncorhynchus mykiss) (Shell Research Ltd., 1986). The only saltwater species reported is the common mullet (Mugil cephalus) which shows a similar sensitivity to the freshwater species, having a 96 h LC50 of 89 mg/L (Crews, 1974).