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EC number: 268-500-3
CAS number: 68109-88-6
Table 1 PII at 24 and 72 hours.
PII = total ÷ 4
Table 2 Individual Scores
The skin irritancy potential of the test material was assessed in a GLP
compliant in vivo study that was based upon the procedure
outlined in the guidelines of the United States EPA, Paragraph 163.81-5
“Primary dermal irritation study”, Federal Register, Vol. 43 No. 163,
August 22, 1978.
Six New Zealand White rabbits were exposed to the test material in an
occlusive fashion for 24 hours on both intact and abraded skin. The skin
reactions were evaluated in accordance with the Draize scale at 24, 48
and 72 hours followed by observations after 4 and 7 days.
Under the conditions of this study, the test material produced marked
irritation to the skin and as such requires classification as “Category
2, H315: Causes skin irritation” with signal word “Warning” in
accordance with EU criteria.
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