Registration Dossier

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

LC50 = >0.09 mg/L (geometric mean of the solubility of the test substance.)  LC50 > water solubility (Aqueous solubility of the test material is between 0.05 and 0.18 mg/L), dioctyltin oxide, OECD 203 and EU Method C.1, Hooftman & de Wolf 2004

Key value for chemical safety assessment

Additional information

The acute toxicity of the test material to fish was determined in a semi-static test conducted in accordance with OECD 203 and EU Method C.1 and in line with GLP in Brachydanio rerio (zebra fish). Due to the insolubility of the test material the study was performed with a water soluble fraction as a limit test. Under the conditions of the study, the 96 h LC50 of the test material was found to be greater than the water solubility of the test material (between 0.05 and 0.18 mg/L under the conditions of this study).


As the study was performed on a read-across substance in the same category as the registered substance (di-n-octyltin oxide), it was assigned a reliability score of 2 (reliable with acceptable restrictions) in accordance with the criteria for assessing data quality as outlined in Klimisch (1997) and considered suitable for assessment as an accurate reflection of the test material.