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EC number: 417-790-1
CAS number: 78418-01-6
In a primary dermal irritation GLP
study performed according to OECD guideline 404, three young adult male
White New-Zealand rabbits were dermally exposed to 0.5 g of ER 195 in
0.5 mL of distilled water for 4 hours to 6.25 cm² of clipped skin.
Animals then were observed for 3 days. Irritation was scored by the
method of Draize (1959).
There was no irritant effect at any
observation time point. In this study, ER 195 is not a dermal irritant
on male rabbits.
Under the test conditions, ER 195 is not
classified as irritating to the skin according to the criteria of Annex
VI to the Directive 67/548/EEC and CLP Regulation (EC) N° (1272-2008).
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