Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Hydrolysis

An experiment was conducted under GLP, and following a guideline similar to EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH). The obtained results demonstrated that the substance is stable as less than 10% of hydrolysis occurred after 5 days.

 

Biodegradation

Three ready biodegradability tests have been performed according to OECD Guideline 301 on MEXORYL SAB. In all studies, biodegradation of MEXORYLSAB was observed. Among 2/3 studies (OECD TG 301D, 301F), MEXORYL SAB was found to be readily biodegradable without fulfilling the 10 -day. In an inherent biodegradation test in accordance with OECD TG 302B, MEXORYL SAB was biodegraded at 90% on Day 28. The reference substance (procedure control) attained 100% of biodegradation on Day 10. The test is considered as valid. Under the condition of the inherent biodegradation testing, MEXORYL SAB is considered as inherently biodegradable.

Adsorption/Desorption

Based on a low Log Kow (0.32), the registered substance is expected not to adsorb strongly. However to address the adsorption behaviour of the ionised and non ionised forms of registered substance, an OECD 121 (GLP compliant) was conducted. The Log Koc was determined to 3.3 for the non ionised form and to 1.3 for the ionised form using the HPLC Method.