Registration Dossier

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study

Data source

Reference
Reference Type:
publication
Title:
IPCS, International Programme on Chemical Safety, Poisons Information Monograph 980, Thiodiglycol
Author:
WHO
Year:
2001
Bibliographic source:
[http://www.inchem.org/documents/pims/chemical/pim980.htm]

Materials and methods

Type of study / information:
Type of experience: Human

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Results:
Based on the structural similarity to ethylene glycol, thiodiglycol may produce depression of the central nervous system, metabolic acidosis and renal failure in severe intoxication.

Applicant's summary and conclusion

Conclusions:
Thiodiglycol may produce depression of the central nervous system, metabolic acidosis and renal failure in severe intoxication.
Executive summary:

Based on the structural similarity to ethylene glycol, thiodiglycol may produce depression of the central nervous system, metabolic acidosis and renal failure in severe intoxication.