Chlorosulphuric acid

Toxicity to microorganisms

Link to relevant study record(s)

Reference

Endpoint:

toxicity to microorganisms, other

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

secondary literature

Justification for type of information:

Data is from secondary source

Qualifier:

according to guideline

Guideline:

other: Refer below principle

Principles of method if other than guideline:

Aim of this study was to determine the effect of test chemical on the Pseudomonas fluorescens.

GLP compliance:

not specified

Analytical monitoring:

no

Vehicle:

not specified

Test organisms (species):

Pseudomonas fluorescens

Test type:

static

Water media type:

freshwater

Reference substance (positive control):

not specified

Key result

Dose descriptor:

EC0

Effect conc.:

8 200 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth inhibition

Remarks on result:

other: test duration was not mentioned in the study

Validity criteria fulfilled:

not specified

Conclusions:

Based on the effects observed on the growth of bacteria Pseudomonas fluorescens, due to the test chemical exposure, no effect were observed at 8200 mg/l.

Executive summary:

Aim of this study was to determine the effect of test chemical on the bacteria Pseudomonas fluorescens. Test conducted under the static system. Based on the effects observed on the growth of bacteria Pseudomonas fluorescens, due to the test chemical exposure, no effect were observed at 8200 mg/l. As less effects were observed on the growth of bacteria, chemical consider to be non toxic.

Description of key information

Aim of this study was to determine the effect of test chemical on the bacteria Pseudomonas fluorescens. Test conducted under the static system. Based on the effects observed on the growth of bacteria Pseudomonas fluorescens, due to the test chemical exposure, no effect were observed at 8200 mg/l. As less effects were observed on the growth of bacteria, chemical consider to be nontoxic.

 

Key value for chemical safety assessment

EC50 for microorganisms:

8 200 mg/L

Additional information

Data from various test chemicals was reviewed to determine the toxic nature of the test chemical on the growth of microorganisms. The studies are as mentioned below:

Aim of this study was to determine the effect of test chemical on the bacteria Pseudomonas fluorescens. Test conducted under the static system. Based on the effects observed on the growth of bacteria Pseudomonas fluorescens, due to the test chemical exposure, no effect were observed at 8200 mg/l. As less effects were observed on the growth of bacteria, chemical consider to be nontoxic.

 

First study was supported by the second experimental data. Aim of this study was to determine the effect of test chemical on the Pseudomonas putida. Test conducted under the static system for 16 hrs. Based on the effects observed on the growth of bacteria Pseudomonas putida, due to the test chemical exposure for 16 hrs the EC10 was observed at >= 1000 mg/l. As less effects were observed on the growth of bacteria, chemical consider to be nontoxic.

 

Similar study was also conducted on the Pseudomonas fluorescens. Aim of this study was to determine the effect of test chemical on the Pseudomonas putida. Test conducted under the static system for 16 hrs. Based on the effects observed on the growth of bacteria Pseudomonas fluorescens, due to the test chemical incubation for 24 hrs the EC0 was observed at 6900 mg/l.

 

Thus based on both studies chemical toxicity value ranges from 6900-8200 mg/l.