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EC number: 447-920-2
CAS number: 897393-42-9
The Klimisch 1 study by Bouwman (2004) performed at NOTOX is considered
the key study. This algal growth inhibition test with the unicellular
green alga Selenastrum capricornutum (Pseudokirchneriella subcapitata),
performed according to ISO Guideline 8692, EU Method C.3 and OECD
Guideline 201, yielded a 72-h NOEC and EC50 (based on growth rate
reduction) of 4.6 and > 100 mg/L, respectively. These values can be used
as key values for PNEC derivation.
A single algal growth inhibition study is available (Bouwman, 2004).
Under the conditions of this study with the unicellular freshwater green
alga Selenastrum capricornutum (Pseudokirchneriella subcapitata), the
substance reduced algal growth rate as well as biomass significantly at
nominally 10 mg/L and higher. The 72-h NOEC, LOEC, EC10 and EC50 based
on algal biomass were 4.6, 10, 4.4 and 44 mg/L, respectively, whereas
the 72-h NOEC, LOEC, EC10 and EC50 based on algal growth rate were 4.6,
10, 20 and > 100 mg/L, respectively. The results of this test are valid
and the study is considered a Klimisch 1 study.
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