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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Specific details on test material used for the study:
Identification: FAT 20010/E Lot. 59015
Appearance: Red powder
Water solubility:
9.3 g/L
Temp.:
20 °C
Remarks on result:
other: pH is not known

Preliminary Visual Estimation of the Water Solubility

Appearance of the test mixtures in the preliminary test

 Amount of the test item in mg  Total volume in ml  Appearance of mixture
 100  10  Undissolved
 100  25  Dissolved
 100  50   Dissolved
 100  100   Dissolved

The preliminary visual experiments showed that the water solubility of the test item is about 5 g/l

Flask-Method

Water solubility of the test item – experiments A to D

Experiment

A

B

C

D (Blank)

Amount of test item(mg)

1000

1000

1000

 ---

Stirring time at 30°C (h)

24

48

72

 72

Measured concentration (μg/ml)

23.44

23.35

23.08

 ---

Aliquot

0.025/10 ml

0.025/10 ml

0.025/10 ml

  

0.025/10 ml

Water solubility (g/l)

9.4

 9.3

 9.2

 ----

Average experiments A to C: 9.3 g/l

Conclusions:
The water solubility cs of the test item at a temperature of 20 °C was determined to (without correction for the purity) be 9.3 g/l.
Executive summary:

The purpose of the study was determination of the water solubility of FAT 20010/E according to the European Commission Regulation (EC) No.440/2008 Part A: methods of determination of physical–chemical properties.A6. Water solubility , flask – method and OECD test guidelines OECD 105 water solubility. Based on the findings of the study, the water solubility cs of the test item at a temperature of 20 °C was determined to (without correction for the purity) be 9.3 g/l.

Description of key information

The water solubility of the test item at a temperature of 20 °C was determined to (without correction for the purity) be 9.3 g/l.

Key value for chemical safety assessment

Water solubility:
9.3 g/L
at the temperature of:
20 °C

Additional information

The purpose of the study was determination of the water solubility of FAT 20010/E according to the European Commission Regulation (EC) No.440/2008 Part A: methods of determination of physical–chemical properties.A6. Water solubility , flask – method and OECD test guidelines OECD 105 water solubility. Based on the findings of the study, the water solubility cs of the test item at a temperature of 20 °C was determined to (without correction for the purity) be 9.3 g/l.