Registration Dossier
Registration Dossier
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EC number: 203-093-8 | CAS number: 103-26-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Methyl cinnamate has a significant inhibitory effect on the growth rate of Pseudokirchneriella subcapitata during the 72‑hour test period. The ErC50 was determined being 7.6 mg/L and the ErC10 was established at 4.0 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 7.6 mg/L
- EC10 or NOEC for freshwater algae:
- 4 mg/L
Additional information
A valid test according to OECD 201 is available for methyl cinnamate. Methyl cinnamate has a significant inhibitory effect on the growth rate of Pseudokirchneriella subcapitata during the 72‑hour test period. The ErC50 was determined being 7.6 mg/L and the ErC10 was established at 4.0 mg/L based on geometric mean measured concentrations.
The losses during the test were considered to be due to adsorption of the test item onto the algae as well as onto the test vessels and degradation. As the test was performed in a closed system losses via volatilisation are expected to be negligible. It was observed that photolytic isomerisation took place during the test and changed the isomeric ratio of the test item from the E-Isomer more to the Z-Isomer of the test substance. These assumptions are based on results of an additional stability trial performed in parallel to the biological test where the test substance was incubated without algae in the dark and only E-methyl cinnamate and no Z-methyl cinnamate was found during the 72h testing period. Therefore, the mean measured concentration of the test item is based on the sum of the two isomers (E-methyl cinnamate and Z-methyl cinnamate).
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