Registration Dossier
Registration Dossier
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EC number: 203-093-8 | CAS number: 103-26-4
Endpoint summary
Administrative data
Description of key information
Additional information
Valid acute toxicity tests with the test substance are available for three freshwater species from three trophic levels. The studies show that fish are the most sensitive species with a LC50 = 2.76 mg/L (geom. mean LC0/LC100 of measured concentrations).
In the static guideline study over 96 hours oily droplets were observed at the surface of solution at all concentrations. The concentrations in test medium significantly decreased over study duration. Therefore, the biological results were based on the arithmetic mean of measured concentrations.
In a semi-static daphnia study over 48 hours an EC50 of 24 mg/L was determined. In the valid static algae study the ErC50 after 72 hours was 7.6 mg/L based on geometric mean measured concentration. The ErC10 was determined to be 4 mg/L.
The lowest L(E)C50 value of the three studies (Fish LC50 = 2.76 mg/L) is used in the hazard assessment and for derivation of aquatic PNECs.
A valid test on the toxicity to microorganisms according to ISO 8192 is available. Methyl cinnamate was shown to inhibit the growth of sludge bacteria and an EC50(3h) = 181 mg/L was determined.
No long-term tests on aquatic toxicity are available, but as the risk assessment based on acute toxicity data demonstrated that there is no risk for the aquatic environment, there is no need to investigate further the effects on aquatic organisms.
Although the substance is considered toxic to aquatic organisms according to GHS (Acute 2), classification according to CLP is not required as methyl cinnamate is readily biodegradable (100% biodegradation in 28 days) and has low potential for bioaccumulation (logPOW 2.86).Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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