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EC number: 434-430-9 | CAS number: -
Stability in organic solvents and identity of relevant degradation products
Administrative data
Link to relevant study record(s)
- Endpoint:
- stability in organic solvents and identity of relevant degradation products
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Testing was conducted between 21 September 2011 and 22 November 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in compliance with agreed protocols, with no or minor deviation from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The feasibility of performing the stability in organic solvent test was conducted by assessment of the solubility of the test item in organic solvent.
- GLP compliance:
- yes (incl. QA statement)
- Test substance stable:
- not determined
- Transformation products:
- not measured
- Conclusions:
- The solubility of the test item was determined to be less than 1.05 mg/l in both xylene and ethanol; therefore it was not possible to perform stability in organic solvent testing.
- Executive summary:
In an assessment of the feasibility of the test, the solubility of the test item was determined visually in xylene and ethanol, using a flask method. The solubility of the test item was determined to be less than 1.05 mg/l in both xylene and ethanol; therefore it was not possible to perform stability in organic solvent testing.
Reference
Results
The flasks were visually examined for the presence of test item by observation of the Tyndall beam effect.
Sample Number |
Observation |
Concentration |
1 |
Tyndall beam effect observed indicating the presence of excess undissolved test item. |
1.05 |
2 |
Tyndall beam effect observed indicating the presence of excess undissolved test item |
1.05 |
The solubility of the test item was determined to be less than 1.05 mg/l in both xylene and ethanol; therefore it was not possible to perform stability in organic solvent testing.
Description of key information
The solubility of the test item was determined to be less than 1.05 mg/l in both xylene and ethanol; therefore it was not possible to perform stability in organic solvent testing.
Additional information
In an assessment of the feasibility of the test, the solubility of the test item was determined visually in xylene and ethanol, using a flask method. The solubility of the test item was determined to be less than 1.05 mg/l in both xylene and ethanol; therefore it was not possible to perform stability in organic solvent testing.
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