Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

In an LLNA study in mice, a stimulation index of greater than 3 was recorded for the three concentrations of the test material (10%, 25% and 50%). No signs of systemic toxicity were observed in test or control animals during the study period. Very dark re-coloured staining of the fur was noted in test animals one hour post dosing throughout the study period. Based on the results of this study, the test substance is considered a skin sensitizer.

Migrated from Short description of key information:
An LLNA study in mice with the test substance is available. The test was performed according to OECD guidelines and GLP.

Justification for classification or non-classification

Based on the above mentioned result, the substance shall be classified for skin sensitization:

- according to the CLP Regulation (EC) 1272/2008: Skin Sens. 1, H317

- and according to the Dangerous Substance Directive 67/548/EC: Xi, R43