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EC number: 213-697-3 | CAS number: 1003-03-8
In the key study, the test item was tested for its mutagenic potential based on the ability to induce point mutations in selected loci of several bacterial
strains, i .e . Salmonella typhimurium TA 1535, TA 100, TA 1537, TA 98 and Escherichia coli E . coli WP2 uvrA, in a reverse mutation assay. Standard plate test (SPT) and preincubation test (PIT) both with and without metabolic activation (Aroclor-induced rat liver S-9 mix). The dose range in the standard plate test was 20 µg - 5000 µg/plate. According to the results of the present study, the test item is not mutagenic in the Salmonella typhimurium/Escherichia coli reverse mutation assay.
In the supporting study, the test item was tested in Salmonella typhimurium TA1535 in an Ames test. The test item is negative without metabolic activation.
Based on the results, the substance was not classified according to Regulation (EC) No 1272/2008 and Directive 67/548/EEC (DSD).
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