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EC number: 213-697-3 | CAS number: 1003-03-8
Toxicity to fish
Based on the results of a static test with the zebrafish (Danio rerio) following OECD 203, the 96h LC50 as the geometric mean value was determined to be at 197 mg/L, based on arithmetic mean concentrations of pH adjusted test solutions (BASF AG, 1998). The test was performed under GLP, the test concentrations were analytically verified and all validity criteria fulfiled. There is a geometric mean value (LC50) for non pH-adjusted test solutions at 124 mg/L but the pH effect is obvious in this case. Therefore, the substance is with high probability acutely not harmful to fish.
Toxicity to aquatic invertebrates
In a static study following EC method C.2 with Daphnia magna, the 48h EC50 (immobilization) was determined to be 52.81 mg/L based on nominal concentrations without pH adjustment (BASF AG, 1987). The non-GLP study fulfilled all validity criteria, there was no analytical monitoring during the test. Using the EC50 value, cyclopentylamine is acutely harmful to aquatic invertebrates. There is no data available on log-term effects on aquatic invertebrates.
Toxicity to aquatic algae
In a static study following OECD 201 with Desmodesmus subspicatus, the 72h ErC50 was determined to be 87.4 mg/L (ErC10 = 40.9 mg/L) based on nominal concentrations (BASF AG, 1987) without pH adjustment. The non-GLP study does not fulfill all recent validity criteria. The mean specific growth rate, which is used for the EC50/EC10 and the hazard assessment fulfilled the validity criteria. Therefore, the test can be used for the assessment. There was no analytical monitoring during the test. Based on the EC50 value, cyclopentylamine is acutely harmful to algae.
Toxicity to microorganisms
There is a growth inhibtion test with Pseudomonas putida according to Bringmann-Kuehn available. The 17h EC10 was determined to be 68.3 mg/L (BASF AG, 1987). This test is used deriving the PNEC STP since the short-term respiration test (similar to OECD 209) was performed with activated industrial sludge (and not domestic), the 30min EC20 of >663 mg/L (BASF AG, 1988) could not be used for the PNEC assessment. However, since the EC20 on acitivated sludge is higher than the highest tested concentration, the inhibition of the degradation activity of activated sludge in wwtps is not likely when cyclopentylamine is introduced in appropriately low concentrations.
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