Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

For (hydroxyethyl) urea, data are available for fish, daphnia and algae. An overview of all results is presented in the table below.The exposure concentrations were not quantified in the short term tests but in the semi-static long-term study with daphnia it was shown that the substance remains stable at least for 72 hours. It is therefore considered justified to use the nominal test concentrations to derive the dose-response relationship for the long-term daphnia test but also for the short-term studies.


An overview of all results is presented in the table below: 



Daphnia magna

OECD 202, EC C.2

KEY Study

ABC laboraties 2001

48h-EC50: >1000 mg a.i./L

Daphnia magna

OECD 211

KEY Study 

AkzoNobel Environmental Chemistry laboratories 2013

21d-NOECreprod: 71.4 mg a.i./L

21d-NOECbiomass: 7.14 mg a.i./L

Oncorhynchus mykiss

OECD 203

KEY Study


ABC laboratories 2001

96h-LC50: >1000 mg a.i./L


Pseudokirchneriella subcapitata

OECD 201

KEY Study 

ABC laboratories 2001

72h-ErC50: >1000 mg a.i./L

72h-NOErC: 1000 mg a.i./L


Microorganisms, activated sludge

OECD 301B toxicity control

Key Study 

Brixham environmental laboraties 2001

28d NOEC = 28.57 mg a.i./L