Registration Dossier

Administrative data

Description of key information

Read-across from in vivo studies of skin and eye irritation (where cyanuric acid was non-irritating);so the same results can be extrapolated to trisodium cyanurate.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Read-across:

1. Based on the experimental results obtained with the analogue cyanuric acid (72h-primary dermal irritation index (PDII)= 0) , the read-across approach is applied and the 72h-primary dermal irritation index (PDII) for substance trisodium cyanurate is calculated to be 0 (skin irritation).
2. Based on the experimental results obtained with the analogue cyanuric acid (72h-overall irritation score= 0.3) , the read-across approach is applied and the same result can be extrapolated for substance trisodium cyanurate (eye irritation).

Justification for classification or non-classification

In the in vivo skin and eye irritation studies cyanuric acid was non-irritant and therefore requires no classification under DSD or CLP