Registration Dossier
Registration Dossier
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EC number: 221-255-6 | CAS number: 3047-33-4
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
Read-across from two eight day dietary studies in mallard duck and bobwhite quail with the monosodium salt of cyanuric acid.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for birds:
- 12 822 mg/kg food
Additional information
Mallard ducks were exposed to 464, 1000, 2150, 4640 and 10000 ppm nominal concentrations for 5 days and then observed for an additional three days. Negative controls were exposed to a basal diet only. Monosodium cyanurate did not cause any symptoms of toxicity or behavioural abnormalities at the dosage levels tested. There was no mortality at any dosage level, with the exception of an incidental death in the 2150 ppm dosage level. In another study bobwhite quail were exposed to 464, 1000, 2150, 4640 and 10000 ppm dietary concentrations of monosodium cyanurate for 5 days and then observed for an additional three days. Negative controls were exposed to a basal diet only. Monosodium cyanurate did not cause symptoms of the toxicity or behavioural abnormalities at the dosage levels tested. There was no mortality at any dosage level.
Read-across:
1. Based on the experimental results obtained with the analogue monosodium salt of cyanuric acid in (8d-LC50 > 10000 ppm) and the molecular weights, the read-across approach is applied and the 8d-LC50
for substance trisodium cyanurate is calculated to be higher than 12822 ppm (Anas platyrhyncos).
2. Based on the experimental results obtained with the analogue monosodium salt of cyanuric acid (8d-LC50 > 10000 ppm) and the molecular weights, the read-across approach is applied and the 8d-LC50 for substance trisodium cyanurate is calculated to be higher than 12822 ppm (Colinus virginianus).
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