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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

Read-across from algal growth inhibition studies for the monosodium salt of cyanuric acid  freshwater algae and one study with marine algae.

Key value for chemical safety assessment

EC50/LC50 for freshwater algae:
3 095.7 mg/L
EC10, LC10 or NOEC for freshwater algae:
1 433.1 mg/L
EC10, LC10 or NOEC for marine water algae:
128.2 mg/L

Additional information

Read-across:

1. Based on the experimental results obtained with the analogue monosodium salt of cyanuric acid, monohydrate (72h-EbC50= 2700 mg/L, basis for effect: biomass; 96h-EbC50 > 5000 mg/L, basis for effect: biomass; 72h- ErC50 > 5000 mg/L, basis for effect: growth rate; 96h- ErC50 > 5000 mg/L, basis for effect: growth rate; 72h- NOEC = 1250 mg/L, basis for effect: growth rate; 96h- NOEC = 5000 mg/L, basis for effect: growth rate ) and the molecular weights, the read-across approach is applied and the calculated values for substance trisodium cyanurate, under test conditions, are the following (for Navicula pelliculosa):

72h-EbC50= 3095.7 mg/L, basis for effect: biomass

96h-EbC50 > 5708.4 mg/L, basis for effect: biomass

72h- ErC50 > 5708.4 mg/L, basis for effect: growth rate

96h- ErC50 > 5708.4 mg/L, basis for effect: growth rate

72h- NOEC = 1433.1 mg/L, basis for effect: growth rate

96h- NOEC = 5708.4 mg/L, basis for effect: growth rate

2. Based on the experimental results obtained with the analogue monosodium salt of cyanuric acid (72h-EC50 > 100 mg/L and 72h-NOEC = 100 mg/L) and the molecular weights, the read-across approach is applied and the 72h-EC50 and 72h-NOEC for substance trisodium cyanurate are calculated to be higher than 128.2 and 128.2, respectively (for Skeletonema costatum).

3. Based on the experimental results obtained with the analogue cyanuric acid (96 h-EC50=712 mg/L, basis for effect: in vivo chlorophyll; and 96 h-EC50=655 mg/L,. basis for effect: cell number) and the molecular weights, the read-across approach is applied and the 96 h-EC50 for substance trisodium cyanurate is calculated to be 1075.7 mg/L (basis for effect: in vivo chlorofill) and 989.6 mg/L (basis for effect: cell number) (for Selenastrum capricornutum (new name: Pseudokirchnerella subcapitata)).