Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 268-215-4 | CAS number: 68037-92-3 This substance is identified by SDA Substance Name: C16-C22 alkyl amine and SDA Reporting Number: 21-029-00.
Endpoint summary
Administrative data
Description of key information
C16-22-(even numbered)alkylamines (CAS no 68037-92-3), which is solid at room temperature was dissolved in ethanol. Water was added and pH was determined to 11.5 in a 5 w/w-% solution of the test substance in water/ethanol (50:50). Based on the high pH and according to CLP the C16-22-(even numbered)alkylamines (CAS no 68037-92-3) is classified as skin corrosive Category 1 and to cause serious eye damage Category 1.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no study available
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
As the pH of C16-22-(even numbered)alkylamines (CAS no 68037-92-3) is determined to be 11.5 the substance is considered to be corrosive to skin and cause serious eye damage in accordance to the CLP legislation.
Justification for selection of skin irritation / corrosion endpoint:
According to the REACH legislation Annex VII, a skin irritation or corrosion study does not need to be conducted on the substance if the criteria are met for classification as corrosive to the skin or irritating to eyes. As described in IUCLID section 4.20, the pH of C16-22-(even numbered)alkylamines (CAS no 68037-92-3) is determined to 11.5 in a 5 w/w-% solution of the test substance in water/ethanol (50:50) and according to the CLP legislation the substance is classified as corrosive to skin based on the high pH. No skin irritation or corrosion study is therefore performed.
Justification for selection of eye irritation endpoint:
According to the REACH legislation Annex VIII, an in vivo eye irritation study does not need to be conducted if the substance has a pH ≥ 11.5. As described in IUCLID section 4.20, the pH of C16-22-(even numbered)alkylamines (CAS no 68037-92-3) is determined to 11.5 in a 5 w/w-% solution of the test substance in water/ethanol (50:50). No eye irritation study is therefore performed.
Justification for classification or non-classification
According to the CLP legislation, the substance C16-22-(even numbered)alkylamines (CAS no 68037-92-3) is considered to be skin corrosive Category 1 and to cause serious eye damage Category 1, based on the high pH value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
