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EC number: 201-903-4
CAS number: 89-39-4
Nitrohydrochinondimethylether was tested for skin irritating or skin
corrosive properties according to OECD 404. Following this protocol 500
mg test substance mixed with 0,2 ml Polyethylenglycol 400 were applied
to the shaved skin of 3 New Zealands White rabbits. After 4 h exposure
time the semiocclusive patch was removed. Residual test substance was
removed with lukewarm tap water. Animals were examined for signs of skin
irritation and/or corrosion at 30-60 min, 24, 48, and 72 h after patch
removal. Mean scores (mean of 24, 48, and 72h) were calculated for
oedema and erythema for each rabbit.
Based on the findings in this test the test substance is neither skin
irritating nor skin corrosing.
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