Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 229-222-8 | CAS number: 6440-58-0
In Annex IX of Regulation (EC) No 1907/2006, it is laid down that short-term toxicity to terrestrial organisms shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects of the substance and/or relevant degradation products on terrestrial organisms. Column 2 of Annex IX states that studies do not need to be conducted if direct and indirect exposure of the soil compartment is unlikely.
For information, there are no reliable toxicity data for soil-dwelling organisms relating to DMDMH. However, reliable toxicity data for terrestrial organisms is available for DMH, the hydrolysis product of DMDMH. DMDMH readily undergoes hydrolysis to DMH and therefore data are provided for both substances when available. In the case of long-term testing, the data on DMH are considered more relevant for environmental fate and ecotoxicology and are provided in this dossier for information.
It can be concluded that short-term toxicity testing of terrestrial organisms is not required based on the unlikely direct or indirect exposure of soil organisms to the DMDMH product or its degradation product (DMH). Based on the unlikely direct exposure to soil organisms, rapid biodegradability in the environment and the additional evidence of no toxicity observed in soil microbes, plants or soil macroinvertebrates in long- and short-term toxicity testing of the breakdown product.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again