Registration Dossier
Registration Dossier
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EC number: 500-464-9 | CAS number: 160901-27-9 1 - 2.5 moles ethoxylated
Endpoint summary
Administrative data
Description of key information
Additional information
The assessment is based on the data currently available. New studies, based on the category review and the final decisions issued for some of the category substances, which are also relevant for this assessment, are currently being conducted. The hazard assessment with respect to aquatic toxicity will be updated once all ongoing studies have been finalised.
The alkyl ether sulfates grouped within the AES category show similar structural, physico-chemical, environmental and toxicological properties. The approach of grouping different AES for the evaluation of their effects on human health and the environment was also made by the Danish EPA [1] and HERA [2], supporting the read across approach between structurally related AES.
The aquatic toxicity of the alkyl ether sulfates has been evaluated in studies on fish, invertebrates and algae as well as microorganisms. In most of the given studies AES were tested as sodium salts. As the cation counterpart of the AES anions is not expected to influence the ecotoxicological profile of the substance, read-across is possible between all comparable mixtures independent from the cation (e. g. sodium, magnesium, ammonium, MIPA; for details see category justification). Based on the available experimental data it is assumed that with increasing chain lengths also the toxicity increases.
Since carbon chain lengths ≤ C10 are the main components of the AES (C9 -11, 1 -2.5EO) NH4 (CAS 160901 -27 -9) mixture a read-across approach from structural comparable AES (C8-10, 1-2.5EO) mixtures was applied. To cover the acute toxicity of aquatic invertebrates a study results from the mixtures AES (C8-10, 1-2.5EO) Na is available. In this study an EC50 of 91 mg a.i./L for Daphnia magna was determined. The chronic invertebrates study was conducted with the AES (C8-10, 1-2.5EO) NH4 (CAS 160901-28-0) mixture. Based on reproduction a NOEC of 5.3 mg a.i./L for Daphnia magna was found. The algae endpoint was covered by a read-across approach from AES (C8-10, 1-2.5EO) NH4 (CAS 160901-28-0). In this study a NOEC value of 31.3 mg a. i /L was reported and the corresponding EC50 value was assumed to be > 100 mg a.i./L.
To cover the acute toxicity on fish a read-across approach from AES (12-14, 1-2.5EO) Na (CAS 68891-38-3) was performed as a worst case scenario.The LC50 value determined in this read-across study was 7.1 mg a.i./L for fish.
[1] Danish EPA - Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products (2001). Environmental Project No. 615, pp. 24-28
[2] HERA - Human & Environmental Risk Assessment on ingredients of European household cleaning products (2004).Alcohol Ethoxysulphates (AES).
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