Registration Dossier
Registration Dossier
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EC number: 252-669-5 | CAS number: 35674-68-1
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
Zinc bis[12-hydroxyoctadecanoate]:
Toxicity data are not available for zinc bis[12-hydroxyoctadecanoate]. A read-across is made to insoluble/ slightly soluble zinc substances.
Zinc:
Twenty-four NOEC/EC10 values are available for toxicity of Zn to reproduction of terrestrial arthropods, representing 2 different species and ranging between 14.6 and 1000 mg Zn/kg dw (both for Folsomia candida).
Key value for chemical safety assessment
Additional information
Zinc bis[12-hydroxyoctadecanoate]:
As terrestrial toxicity data are not available for zinc bis[12-hydroxyoctadecanoate],a read-across to insoluble/ slightly soluble zinc substances is made. It is assumed that upon dissolution or intake zinc bis[12-hydroxyoctadecanoate] is changed in part to ionic zinc and that only ionic zinc is determining biological activities.The ecotoxic potential of the fatty acid chain, i.e. 12-hydroxystearate, is assumed to be negligible. Fatty acids are generally not considered to represent a risk to the environment, which is reflected in their exclusion from REACH registration requirements (c.f. REACH Annex V (Regulation (EC) No 987/2008)).For a comprehensive overview of the toxicity of zinc, see the hazard assessment of "Zinc" within the framework of Regulation (EC) No 1907/2006 in Appendix 1 of the CSR and cited in excerpts below.
ZINC:
In total 61 individual high quality NOEC or EC10 values for reproduction of terrestrial invertebrates are selected for the PNEC derivation. Twenty-four NOEC/EC10 values are available for toxicity of Zn to reproduction of terrestrial arthropods, representing 2 different species and ranging between 14.6 and 1000 mg Zn/kg dw (both for Folsomia candida; Lock and Janssen, 2001c and Lock et al., 2003).
All toxicity data are expressed as added Zn concentration in soil, based on either the nominal dose added or on measured, background corrected soil Zn concentrations.
[Lock et al. (2003). Laboratory zinc ecotoxicity testing for soil invertebrates. Testing laboratory: Ghent University Laboratory of Environmental Toxicology and Aquatic Ecology Jozef Plateaustraat 22, B-9000 Gent Belgium. Report no.: ZEH-SO-3.]
[Lock K. & Janssen C. R. (2001). Modeling zinc toxicity for terrestrial invertebrates. Environmental Toxicology and Chemistr y, Vol. 20, No. 9, pp. 1901–1908, 2001]
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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