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EC number: 252-669-5
CAS number: 35674-68-1
Zinc bis[12-hydroxyoctadecanoate]:Bioaccumulation of zinc bis[12-hydroxyoctadecanoate] in animals and biomagnification (i.e. accumulation and transfer through the food chain) is not considered relevant.ZINC:Zinc is an essential element which is actively regulated by organisms, so bioconcentration/bioaccumulation is not considered relevant.
on read-across of zinc bioaccumulation data and the fact that zinc
bis[12-hydroxyoctadecanoate] is readily biodegradable, bioaccumulation
and biomagnification are not expected to be relevant for zinc
bis[12-hydroxyoctadecanoate]. For a comprehensive overview of the
bioaccumulation of zinc or the lack thereof, see the hazard assessment
of "Zinc" within the framework of Regulation (EC) No 1907/2006 in
Appendix 1 of the CSR and cited in excerpts below.These
conclusions are similar to the conclusions for a structural analogue
from the EU RAR Zinc distearate (CAS-No.: 557-05-1 & 91051-01-3
EINECS-No.: 209-151-9 & 293-049-4) Part 1 - Environment (Final report
R074_0805_env, May 2008
on data on bioaccumulation of zinc in animals and on biomagnification
(i.e. accumulation and transfer through the food chain), secondary
poisoning is considered to be not relevant in the effect assessment of
zinc..." "Distearate is not expected to bioaccumulate, knowing that
fatty acids will degrade by the β oxidation pathway."
Bioaccumulation is not considered relevant
for essential elements because of the general presence of homeostatic
control mechanisms. The data from a field food chain transfer study
indicate that bioconcentration of zinc is indeed very low. It is in all
cases also lower in contaminated soil, as compared to control soil.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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