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EC number: 231-845-5 | CAS number: 7758-95-4
Experiments were conducted to measure the GI absorption and elimination of a single oral dose of lead-210 acetate in infant and adult rhesus monkeys. Urinary and fecal excretion of absorbed lead were examined for 23 days post-exposure. Infant monkeys eliminated less and absorbed more of the administered lead. Adult animals excreted more absorbed lead in feces, whereas urinary excretion was similar between adults and infants. Increased absorption of administered lead and reduced fecal excretion of absorbed lead resulted in a greater body burden of lead in infant animals compared to adults. Blood lead concentrations were inversely correlated with body burden and percent absorption of ingested lead.
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