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EC number: 247-119-6
CAS number: 25586-42-9
Single samples of 0.1 mL of the undiluted test item were instilled into
one eye of each of three male New Zealand white rabbits. The other eye
served as internal control. Observations were made 1, 24, 48 and 72
hours after instillation. Instillation of the test substance resulted in
a slight irritation of the conjunctivae, which consisted of redness
(mean score 24 - 72 h: 0.43, maximal value: 2 after 1 h), chemosis (mean
score 24 - 72 h: 0, maximal value: 1 after 1 h) and minimal discharge.
The irritation completely resolved within 72 hours in one animal and
within 48 hours in the other two animals.
Based on these results the test item does not have to be classified and
has no obligatory labelling requirement for eye irritation according to
the Regulation (EC) No 1272/2008
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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