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Environmental fate & pathways

Hydrolysis

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Description of key information

Information from non-guideline experiments and from surrogate substances is available, which in a weight-of-evidence evaluation shows rapid hydrolysis of TTP to cresol and other degradation products. 

Key value for chemical safety assessment

Half-life for hydrolysis:
18 h
at the temperature of:
20 °C

Additional information

No OECD 111 Guideline study was performed.

But information from non-guideline experiments and from surrogate substances is available:

- Evaluation of the EU TC NES Subgroup on PBT / vPvB substances:

1. Diisodecyl phenyl phosphite: This substance is closely related to tritolyl phosphite (TTP). An OECD 111 study is reported in the TC NES report, on which basis the TC NES Subgroup concluded that the substance is hydrolysed rapidly and should not be considered persistent.

2. Triphenyl phosphite (TPP): In the same report results from a hydrolysis study on TPP, which is also closely related to TTP, are evaluated. Based on these results the TC NES Subgroup concluded that TPP is hydrolytically unstable and should not be considered persistent.

-       Investigations with NiL4 on its stability in water/THF:

Analytical results from laboratory tests applying semi-quantitative HPLC show that NiL4, when dissolved in a THF/water solution, decomposes within several hours to give free TTP ligand, TTP hydrolysis products, cresol and Ni metal.       

-       Investigations on stability of NiL4 in acetonitril/water

In experiments undertaken to establish an analytical method for NiL4, the substance TTP and its degradation product cresol were detected with UPLC in acetonitril/water.

Taking into consideration this information in a weight-of-evidence evaluation it can be concluded that rapid hydrolysis of the submission substance occurs in aquatic environments at ambient temperature. TTP is degraded (via phosphites containing one or two organic residues) to p-cresol.

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