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Diss Factsheets
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EC number: 416-530-4 | CAS number: 178949-82-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993-04-23 to 1993-05-27
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
- Deviations:
- no
- GLP compliance:
- yes
- Key result
- Medium:
- standard fat
- Solubility:
- <= 0.4 mg/100 g solvent
- Temp.:
- 37 °C
- Test substance stable:
- yes
- Conclusions:
- In a GLP study conducted according to OECD Guideline 106, the solubility of trisodium EDDS in a standard fat was up to 4 mg/kg at 37°C
- Executive summary:
In a GLP study conducted according to OECD Guideline 106, the solubility of trisodium EDDS in a standard synthetic fat (HB307) was determined by stirring the test material (100 or 400 mg) with the fat solvent (50 or 25 mL respectively) at 37oC for up to 48 h. The concentration of the test material in the fat phase was measured by HPLC.
The analysed concentrations of trisodium EDDS varied from 0.09 to 3.57 mg/kg. Due to the significant variation between measurements, the fat solubility was taken to be equal to or less than 3.57 mg/kg (the highest concentration analysed).
Reference
Description of key information
In a GLP study conducted according to OECD Guideline 106, the solubility of trisodium EDDS in a standard fat was up to 4 mg/kg at 37°C.
Key value for chemical safety assessment
- Solubility in mg/100g standard fat:
- 0.4
- At the temperature of:
- 37 °C
Additional information
In a GLP study conducted according to OECD Guideline 106, the solubility of trisodium EDDS in a standard synthetic fat (HB307) was determined by stirring the test material (100 or 400 mg) with the fat solvent (50 or 25 mL respectively) at 37oC for up to 48 h. The concentration of the test material in the fat phase was measured by HPLC.
The analysed concentrations of trisodium EDDS varied from 0.09 to 3.57 mg/kg. Due to the significant variation between measurements, the fat solubility was taken to be equal to or less than 3.57 mg/kg (the highest concentration analysed) (de Vries, 1993c).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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