Reaction mass of 1,4-bis(methoxymethyl)benzene, 1,6-dihydroxynaphtalene and Epichlorohydrin

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

03 July 2019 to 04 July 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

capillary method

Specific details on test material used for the study:

No further details specified in the study report

Key result

Melting / freezing pt.:

> 45.3 - < 45.9 °C

Atm. press.:

> 98.1 - < 98.3 kPa

Decomposition:

yes

Decomp. temp.:

50 °C

TEST PARAMETERS AND CONDITIONS

The tests were carried out at air atmospheric pressure (98.1 – 98.3 kPa) and room temperature (approximately 20°C) using a digital melting point device (Büchi B540 Melting Point Unit, calibrated) with a temperature range up to 400°C (673 K).

CHECKING OF THE MELTING POINT TESTER

Before the test item analysis, the proper performance of the instrument was checked by measuring the melting point of Vanillin, Phenacetin and Caffeine. The block was heated at a rate of 0.5°C/minute from a pre-set temperature 5°C lower than the certified melting point values.

Measured reference substances on 03 July 2019

Chemical name	Supplier	Batch No.	Expiry date	Certified melting point value [°C]	Mean of the measured melting point* [°C]
Vanillin	VWR	170115	30 April 2022	82.5 ± 0.3	82.4 ± 0.0
Phenacetin	VWR	180145	31 May 2023	135.8± 0.3	135.5 ± 0.0
Caffeine	VWR	180164	30 June 2023	236.8± 0.3	236.7 ± 0.3

*Mean of three parallel measurements with their 95% confidence interval

The measured values of the reference substances were determined to be in the required range.

Measured temperatures at the beginning of the melting of the test item (three experiments (I, II, III) with three parallel samples each (1, 2, 3) 

Measured temperatures at the final stage of the melting [°C]
I / 1	I / 2	I / 3	II / 1	II / 2	II / 3	III / 1	III / 2	III / 3	Mean	St. Dev
45.5	45.5	45.5	45.9	45.8	45.8	45.3	45.3	45.3	45.5	0.24

 

 

Measured temperatures at the final stage of the melting of the test item (three experiments (I, II, III) with three parallel samples each (1, 2, 3)

Measured temperatures at the final stage of the melting [°C] *
I / 1	I / 2	I / 3	II / 1	II / 2	II / 3	III / 1	III / 2	III / 3	Mean	St. Dev
63.5	63.5	63.5	66.2	65.5	65.5	64.0	63.9	63.9	64.4	1.05

 

*Please note that the final stage of the melting was only apparent, due to colour change was occurred from about 50°C, before the test item was completely melted. It may indicate decomposition, therefore, these measured temperatures were reported, but they were not considered in the evaluation.

Conclusions:

The temperature at the beginning of the melting of CAS 577978-76-8 was found to be approximately 45.5 °C, i.e. 318.7 K. From about 50°C the colour of the test item became darker, then the test item apparently melted.
Due to the observed changes during the melting, no exact melting (softening) range was identified.

Executive summary:

For the determination of the melting point or melting (softening) range, the capillary method using a metal block was applied.

Using a linear heating rate of 0.5°C/minute, the temperature at the beginning of the melting of CAS 577978-76-8 was found to be approximately 45.5 °C, i.e. 318.7 K. From about 50°C the colour of the test item became darker, then the test item apparently melted.

Due to the observed changes during the melting, no exact melting (softening) range was identified.

Description of key information

The temperature at the beginning of the melting of CAS 577978-76-8 was found to be approximately 45.5 °C, i.e. 318.7 K. From about 50°C the colour of the test item became darker, then the test item apparently melted.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

45.5 °C

Additional information

Due to the observed changes during the melting, no exact melting (softening) range was identified.