Benzyl 2-methoxy-4-prop-1-enylphenyl ether

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: Knudsen cell

Test material

Test material information

Constituent 1

Reference substance name:

Benzyl 2-methoxy-4-prop-1-enylphenyl ether

EC Number:

204-370-6

EC Name:

Benzyl 2-methoxy-4-prop-1-enylphenyl ether

Cas Number:

120-11-6

Molecular formula:

C17H18O2

IUPAC Name:

benzyl 2-methoxy-4-prop-1-enylphenyl ether

Results and discussion

Vapour pressure

Vapour pressure 1

Key result

Test no.:

#1

Temp.:

20 °C

Vapour pressure:

0.002 Pa

Vapour pressure 2

Key result

Test no.:

#2

Temp.:

20 °C

Vapour pressure:

0.002 Pa

Vapour pressure 3

Key result

Test no.:

#1

Temp.:

25 °C

Vapour pressure:

0.003 Pa

Vapour pressure 4

Key result

Test no.:

#2

Temp.:

25 °C

Vapour pressure:

0.004 Pa

Applicant's summary and conclusion

Conclusions:

Trial Vapour pressure at 293.15 K Vapour pressure at 298.15 K
1 1.62 x 10-3 Pa 3.35 x 10-3 Pa
2 1.91 x 10-3 Pa 3.94 x 10-3 Pa
Mean 1.77 x 10-3 Pa 3.65 x 10-3 Pa

The test item did not change in appearance under the conditions used in the determination.

Executive summary:

Introduction.A study was performed to determine the vapour pressure of the test itemBENZYL ISO EUGENOL.The method followed was designed to be compliant with the OECD guideline for the Testing of Chemicals No. 104, "Vapour pressure" (23 March 2006) and theCommission Regulation No 440/2008 on test methods (last Adaptation to Technical Progress by Commission Regulation (EU) 2017/735 of 14 February 2017), Method A.4 (last updated by Regulation (EC) No 761/2009).

Testing was conducted from 3 October 2018 to 9 October 2018.

 

Methods.In this dynamic method, the mass of the test substance flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions was determined at various specified temperatures (from 61.0°C to 111.4°C). The Hertz-Knudsen equation was used to calculate the vapour pressure corresponding to the mass loss rate.

The Log₁₀(Vapour Pressure (Pa)) was plotted against 1/T (K) and a linear function was obtained. With this equation, the vapour pressure has been calculated for temperatures of 20°C and 25°C.

 

Results and Conclusion.Two trials were conducted and five points were recorded for each trial.

Log₁₀(Vapour Pressure (Pa)) was plotted against reciprocal temperature and values of vapour pressure were calculated at 20°C and 25°C with the linear function parameters (slope and intercept):

 

Trial	Vapour pressure at 293.15 K	Vapour pressure at 298.15 K
1	1.62 x 10^-3Pa	3.35 x 10^-3Pa
2	1.91 x 10^-3Pa	3.94 x 10^-3Pa
Mean	1.77 x 10^-3Pa	3.65 x 10^-3Pa

 

Calculated values respect validity criteria (less than 20% of difference) and the linear functions obtained own a correlation coefficient R² over 0.95.

Moreover the calculated values showed good correspondence with the experimentally determined ones.

In conclusion, the vapour pressure ofBENZYL ISO EUGENOLis 1.77 x 10^-3Pa at 20°C and 3.65 x 10^-3Pa at 25°C.