Registration Dossier

Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
other: Weight-of-evidence
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Weight of evidence assessment based on the UCVB components and QSAR estimates
Justification for type of information:
No data are available for "Reaction product of saturated palm kernel fatty acids and oxybispropanediol". The bioaccumulation of this substance is therefore assessed in a weight of evidence analysis based on QSAR estimates for the UVCB components supported by analogue analysis of triglycerides.

Data source

Reference
Reference Type:
other: Weight-of-evidence documentation report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
BCF is derived on the basis of a weight-of-evidence analysis.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: Paste
Details on test material:
Same ID as the registered substance

Results and discussion

Bioaccumulation factor
Key result
Temp.:
ca. 25 °C
pH:
7
Type:
BCF
Value:
< 500 dimensionless
Basis:
whole body w.w.
Calculation basis:
steady state

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
Based on a weight-of-evidence approach it is concluded that the compound “Reaction product of saturated palm kernel fatty acids and oxybispropanediol” has a BCF below 500. Based on the BCF the substance does not have potential to bioaccumulate.
Executive summary:

“Reaction product of saturated palm kernel fatty acids and oxybispropanediol” is a UVCB substance.

BCF/BAF calculations on all identified constituents in the UVCB substance resulted in a BCF between 3 and 515 with a concentration averaged BCF well below 500.

Based on a weight-of-evidence approach it is concluded that the compound “Reaction product of saturated palm kernel fatty acids and oxybispropanediol” has a BCF below 500. Based on the BCF the substance does not have potential to bioaccumulate.