Registration Dossier

Manufacture, use & exposure

Uses at industrial sites

Uses at industrial sites

Registration/ Notification status for the use:
use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Use name:
Use of Ceftazidime dihydrochoride intermediate
Contributing activity / technique for the environment
Name of activity / technique:
Use of Ceftazidime dihydrochoride as an intermediate
Environmental release category (ERC):
ERC6a: Use of intermediate
Contributing activity / technique for workersopen allclose all
Name of activity / technique:
WCS IU-1: Charging of substance into reactor
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Name of activity / technique:
WCS IU-2: Use as an intermediate and consumption
Process category (PROC):
PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
Product category used:
PC 29: Pharmaceuticals
Sector of end use:
SU 9: Manufacture of fine chemicals
Subsequent service life relevant for this use:
no
Related assessment:
use assessed in an own CSR

Contributing scenario for the environment (related to workers activities)

Conditions of use for the environment

Conditions and measures related to Biological Sewage Treatment Plant

Biological Sewage Treatment Plant (STP):
no

Conditions and measures related to external treatment of waste (including article waste)

Particular considerations on the waste treatment operations:
no

Other conditions affecting environmental exposure

OtherConditionsEnvirExpRepopen allclose all

Releases to waste and the environment

Release to the environment

ReleaseEnvirRepopen allclose all
Release from the site to::
surface water
Release estimation method:
estimated release factor
Remarks:
Controlled discharge
Release from the site to::
ambient air
Release estimation method:
estimated release factor
Remarks:
Srubber
Release from the site to::
non-agricultural soil
Release estimation method:
estimated release factor
Remarks:
Controlled discharge

Release to external waste

Exposure of the environment

PECopen allclose all
Exposed compartment:
freshwater
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
sediment (freshwater)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
marine water
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
sediment (marine water)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
sewage treatment plant
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
air
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
predators' prey (freshwater)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
predators' prey (marine water)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
top predators' prey (marine water)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Exposed compartment:
predators' prey (terrestrial)
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES

Exposure of humans via the environment

Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
ContribScenWorkersRepopen allclose all

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Physical form of the used product:
solid (very dusty form)

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechCondRepopen allclose all
Effectiveness
Route affected:
inhalation
EffectivenessRepopen allclose all
Route affected:
inhalation
Route affected:
dermal

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
dermal
Effectiveness
Route affected:
inhalation

Other conditions affecting workers exposure

Place of use:
indoor

Exposure of workers

Exposure estimation
Type of exposure:
inhalation (external) short-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Physical form of the used product:
liquid

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechCondRepopen allclose all
Effectiveness
Route affected:
inhalation
EffectivenessRepopen allclose all
Route affected:
inhalation
Route affected:
dermal

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
dermal
Effectiveness
Route affected:
inhalation

Other conditions affecting workers exposure

Place of use:
indoor

Exposure of workers

Exposure estimation
Type of exposure:
inhalation (external) short-term exposure
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers