Registration Dossier
Registration Dossier
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EC number: 205-119-3 | CAS number: 133-74-4
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
No data are available for the substance. Experimental reliable data are available for a structural analogue: 2-Amino-5-chloro-4-methylbenzenesufonic acid, which was not mutagenic for S. typhimurium TA100, TA1535, TA98, TA1537 and E. coli WP2 uvrA with or without exogenous metabolic activation up to 5000 μg/plate. However, this chemical induced chromosomal aberrations with or without exogenous metabolic activation at concentrations of 2.5 and 2.0 mg/ml, respectively. The chemical did not induce polyploidy under the test conditions applied. Since lowering pH by the test substance might have caused the chromosomal aberrations, data available are inconclusive.
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Overall, data are deemed to be inconclusive for classification.
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