1,4-Dioxaspiro[4.5]decane, 8-[4-(4-methylphenyl)-3-cyclohexen-1-yl]-

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 2017-09-27 to 2017.10.05

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)

Deviations:

no

GLP compliance:

no

Type of method:

Laser scattering/diffraction

Type of particle tested:

agglomerate

Type of distribution:

volumetric distribution

Key result

Percentile:

D50

Mean:

9.2 µm

Remarks on result:

other: no SD indicated

Key result

Percentile:

D10

Mean:

2.1 µm

Remarks on result:

other: no SD indicated

Key result

Percentile:

D90

Mean:

30.2 µm

Remarks on result:

other: no SD indicated

Test series 1

D₁₀:         2.0 µm                                                             

D₅₀:         9.3 µm  (Median diameter)                     

D₉₀:         30.8 µm                                                           

 

Test series 2

D₁₀:         2.2 µm                                                             

D₅₀:         9.2 µm  (Median diameter)                     

D₉₀:         29.6 µm                                                           

 

Average

D₁₀:         2.1 µm                                                             

D₅₀:         9.2 µm  (Median diameter)                     

D₉₀:         30.2 µm                                                           

The particle size distribution showed a polymodal distribution. Maxima were observed at approximately 10 um and approximately 200 um and a Shoulder was observed at approximately 1 um.

Conclusions:

The D10, D50 and D90 percentile were determined as D10 = 2.1 µm, D50 = 9.2 µm and D90 = 30.2 µm, respectively.

Executive summary:

A study was conducted according to OECD Test Guideline 110  and ISO 13320 (2009). The D10, D50 and D90 percentile were determined by laser diffraction as D₁₀ = 2.1 µm, D₅₀ = 9.2 µm and D₉₀ = 30.2 µm, respectively.

Description of key information

The D10, D50 and D90 percentile were determined as D₁₀ = 2.1 µm, D₅₀ = 9.2 µm and D₉₀ = 30.2 µm, respectively (reference 4.5-1).

Additional information

A study was conducted according to OECD Test Guideline 110  and ISO 13320 (2009). The D10, D50 and D90 percentile were determined by laser diffraction as D₁₀ = 2.1 µm, D₅₀ = 9.2 µm and D₉₀ = 30.2 µm, respectively.