Registration Dossier

Diss Factsheets

Administrative data

acute toxicity: dermal
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance does not meet the criteria for classification as acute toxicity or STOT SE by the oral route and no systemic effects have been observed in in vivo studies with dermal exposure (e.g. skin irritation, skin sensitisation)
Justification for type of information:
The test item is not harmful after single acute oral administration and no clinical signs were observed in the skin irritation test. The test item is structural highly similar to the LC class compounds shown in this report. There exist no additional structural elements of concern. Therefore, it is justified to use the information provided in this report for filling the endpoint of acute dermal toxicity.

This attached report compiles information on LC class compounds that have been tested for acute dermal toxicity. In these assays no effects have been observed.

Data source

Materials and methods

Results and discussion

Effect levels
Key result
Dose descriptor:
Effect level:
> 2 000 mg/kg bw
Based on:
other: read across information
Remarks on result:
other: see attached justification for details.

Applicant's summary and conclusion